The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Jul. 21, 2014
Applicants:
Sergei M. Gryaznov, San Mateo, CA (US);
Jerry W. Shay, Dallas, TX (US);
Woodring Wright, Arlington, TX (US);
Inventors:
Sergei M. Gryaznov, San Mateo, CA (US);
Jerry W. Shay, Dallas, TX (US);
Woodring Wright, Arlington, TX (US);
Assignees:
GERON CORPORATION, Menlo Park, CA (US);
BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/00 (2006.01); A61K 47/48 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C07H 21/00 (2013.01); A61K 47/48046 (2013.01); C07H 21/04 (2013.01);
Abstract
Compounds of the form O-(x-L)n, where O is an oligonucleoside having at least a plurality of N3'→P5′ thiophosphoramidate (NPS) internucleoside linkages, a conjugated lipid moiety L, and at least one G-rich sequence motif as described, are effective to morphologically alter and reduce adhesion of cancer cells.