The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Jul. 27, 2015
Applicant:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Inventors:
Ronald T. Raines, Madison, WI (US);
Thomas P. Smith, Madison, WI (US);
Assignee:
Wisconsin Alumni Research Foundation, Madison, WI (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07F 5/02 (2006.01); C12N 9/96 (2006.01); C12N 9/22 (2006.01); C12N 11/00 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
C07F 5/025 (2013.01); A61K 47/48061 (2013.01); C12N 9/22 (2013.01); C12N 11/00 (2013.01); C12Y 301/27005 (2013.01); C07K 2319/43 (2013.01); C07K 2319/60 (2013.01);
Abstract
Methods for enhancing cellular uptake of cargo molecules by boronating the cargo molecule, particularly with one or more phenylboronic acid groups. Boronation reagents for reversible boronation of cargo molecules, particularly, cargo molecules having one or more amino groups are provided.