The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2017

Filed:

May. 08, 2014
Applicant:

Merck Patent Gmbh, Darmstadt, DE;

Inventors:

Thomas Fuchss, Bensheim-Auerbach, DE;

Ulrich Emde, Darmstadt, DE;

Hans-Peter Buchstaller, Griesheim, DE;

Werner Mederski, Zwingenberg, DE;

Assignee:

Merck Patent GmbH, Darmstadt, DE;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 513/04 (2006.01); C07D 239/74 (2006.01); C07D 401/10 (2006.01); C07D 403/10 (2006.01); C07D 405/04 (2006.01); C07D 405/14 (2006.01); C07D 417/10 (2006.01); C07D 417/14 (2006.01); C07D 487/04 (2006.01); C07D 491/048 (2006.01); C07D 495/04 (2006.01); C07D 498/08 (2006.01); C07D 471/04 (2006.01); A61K 31/5377 (2006.01); A61K 31/5386 (2006.01); A61K 45/06 (2006.01); C07D 403/14 (2006.01); C07D 473/00 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61K 31/5377 (2013.01); A61K 31/5386 (2013.01); A61K 45/06 (2013.01); C07D 239/74 (2013.01); C07D 401/10 (2013.01); C07D 403/10 (2013.01); C07D 403/14 (2013.01); C07D 405/04 (2013.01); C07D 405/14 (2013.01); C07D 417/10 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 473/00 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01); C07D 495/04 (2013.01); C07D 498/08 (2013.01);
Abstract

The invention relates to novel compounds of the formula (I) which can be used for the inhibition of serine-threonine protein kinases and for the sensitization of cancer cells to anticancer agents and/or ionizing radiation.


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