The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
May. 28, 2015
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Shawn P. Walsh, Bridgewater, NJ (US);
Jared N. Cumming, Garwood, NJ (US);
Shuwen He, Fanwood, NJ (US);
Brandon M. Taoka, Hoboken, NJ (US);
Quang T. Truong, Morganville, NJ (US);
Wen-Lian Wu, Green Brook, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
In its many embodiments, the present invention provides certain C2-carbocyclic iminothiazine dioxide compounds, including compounds Formula (I); or a tautomers thereof, and pharmaceutically acceptable salts of said compounds and said tautomers, wherein R, R, ring A, R, m, ring B, RB, n, ring C, Rand p are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed.