The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2017

Filed:

Dec. 20, 2012
Applicant:

Ono Pharmaceutical Co., Ltd., Osaka-shi, Osaka, JP;

Inventors:

Steve Courtney, Oxfordshire, GB;

Chris Yarnold, Oxfordshire, GB;

Stuart Flanagan, Oxfordshire, GB;

Gareth Brace, Oxfordshire, GB;

John Barker, Oxfordshire, GB;

Osamu Ichihara, Tokyo, JP;

Elise Gadouleau, Oxfordshire, GB;

Anthony Richardson, Oxfordshire, GB;

Takashi Kondo, Osaka, JP;

Akira Imagawa, Osaka, JP;

Shingo Nakatani, Osaka, JP;

Ryo Suzuki, Osaka, JP;

Sho Kouyama, Osaka, JP;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 401/14 (2006.01); C07D 403/14 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 471/04 (2013.01);
Abstract

The present invention provides compounds of the general formula (I), their salts and N-oxides, and solvates and prodrugs thereof (wherein the characters are as defined in the description). The compounds of the general formula (I) are inhibitors of Factor XIa, so that they are useful in the prevention of and/or therapy for thromboembolic diseases.


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