The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2017

Filed:

Sep. 09, 2016
Applicant:

Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);

Inventors:

Rajinder Singh, Belmont, CA (US);

Kin Tso, San Francisco, CA (US);

Jing Zhang, Mercer Island, WA (US);

Matthew Duncton, San Bruno, CA (US);

Salvador Alvarez, Fremont, CA (US);

Rao Kolluri, Foster City, CA (US);

John Ramphal, Union City, CA (US);

Sacha Holland, San Francisco, CA (US);

Assignee:

Rigel Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); A61K 31/506 (2006.01); C07D 405/14 (2006.01); A61K 31/41 (2006.01);
U.S. Cl.
CPC ...
C07D 405/14 (2013.01); A61K 31/41 (2013.01); A61K 31/506 (2013.01); C07D 401/14 (2013.01);
Abstract

This disclosure concerns compounds which are useful as inhibitors of protein kinase C (PKC) and are thus useful for treating a variety of diseases and disorders that are mediated or sustained through the activity of PKC. This disclosure also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.


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