The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 15, 2017

Filed:

May. 29, 2014
Applicant:

Sumitomo Dainippon Pharma Co., Ltd., Osaka, JP;

Inventors:

Hidefumi Yoshinaga, Osaka, JP;

Yoshiharu Uruno, Takarazuka, JP;

Hidetaka Nagata, Suita, JP;

Masakazu Hashimoto, Suita, JP;

Taro Kato, Osaka, JP;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 417/14 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention provides a cyclic aminomethyl pyrimidine derivative and a pharmaceutically acceptable salt thereof with high selectivity for dopamine Dreceptors, which are useful for treating a disease such as attention deficit hyperactivity disorder. Specifically, a compound of formula (1) or a pharmaceutically acceptable salt thereof is provided, wherein n and m are independently 1 or 2; Ris Calkyl group, Ccycloalkyl group, or amino group; Ris hydrogen atom, Calkyl group or the like, provided that when Ris amino group, then Ris hydrogen atom; Rand Rare independently hydrogen atom, or Calkyl group; Rand Rare independently hydrogen atom, fluorine atom or the like; ring Q is an optionally-substituted pyridyl group or an optionally-substituted isoquinolyl group; and the bond having a dashed line is a single or double bond.


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