The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Jun. 13, 2014
Applicant:
Shionogi & Co., Ltd., Osaka-shi, Osaka, JP;
Inventor:
Hiroyuki Kai, Osaka, JP;
Assignee:
SHIONOGI & CO., LTD., Osaka, JP;
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/12 (2006.01); C07D 405/14 (2006.01); C07D 409/14 (2006.01); A61K 31/53 (2006.01); A61P 25/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/12 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01);
Abstract
The present invention provides novel compounds having a P2Xand/or P2Xreceptor antagonistic activity. A compound of Formula (I): wherein Rand R, and Rand Rare taken together to form oxo or the like; Rand Rare hydrogen or the like; n is 1 or the like; Ris aryl or the like; s and s' is 0 or the like; Rand R′ are halogen or the like; Rand Rare hydrogen, alkyl or the like; u is 1 to 4; Ris hydrogen or the like, or its pharmaceutically acceptable salt.