The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Dec. 22, 2014
Applicant:
Hydra Biosciences, Inc., Cambridge, MA (US);
Inventors:
Jayhong A. Chong, Brookline, MA (US);
Magdalene M. Moran, Brookline, MA (US);
Assignee:
Hydra Biosciences, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4245 (2006.01); A61F 6/04 (2006.01); C07D 271/08 (2006.01); C07D 413/14 (2006.01);
U.S. Cl.
CPC ...
C07D 271/08 (2013.01); A61F 6/04 (2013.01); A61K 31/4245 (2013.01); C07D 413/14 (2013.01);
Abstract
The invention provides novel compositions and compounds that inhibit CatSper channel activity, that preferentially inhibits sperm hyperactivity over sperm motility, or both. The compounds of the invention are useful as contraceptive agents that may be adminstered to males, females, or concurrently to both sexual partners. The invention further provides methods of conducting drug discovery business and of conducting a reproductive medicine business. The invention also provides methods of identifying compounds that modulate sperm hypermotility.