The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Aug. 20, 2014
Applicant:
Novartis Vaccines and Diagnostics, Inc., East Hanover, NJ (US);
Inventors:
Silvia Perri, Castro Valley, CA (US);
John Polo, Danville, CA (US);
Yasushi Uematsu, Siena, IT;
Catherine Greer, Oakland, CA (US);
Assignee:
Novartis Vaccines and Diagnostics, Inc., Emeryville, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); C12N 15/86 (2006.01); A61K 39/12 (2006.01); A61K 39/155 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/12 (2013.01); A61K 39/145 (2013.01); A61K 39/155 (2013.01); C12N 15/86 (2013.01); A61K 2039/5252 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/53 (2013.01); A61K 2039/543 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55544 (2013.01); A61K 2039/55566 (2013.01); A61K 2039/70 (2013.01); C12N 2760/16122 (2013.01); C12N 2760/16134 (2013.01); C12N 2760/18322 (2013.01); C12N 2760/18334 (2013.01); C12N 2760/18522 (2013.01); C12N 2760/18534 (2013.01); C12N 2760/18622 (2013.01); C12N 2760/18634 (2013.01); C12N 2770/20022 (2013.01); C12N 2770/20034 (2013.01); C12N 2770/36143 (2013.01); C12N 2830/20 (2013.01); C12N 2830/60 (2013.01); C12N 2840/20 (2013.01); C12N 2840/203 (2013.01);
Abstract
Described herein are compositions and methods for stimulating an immune response to one or more proteins derived from one or more respiratory pathogens. In particular, the invention relates to alphavirus replicons, alphavirus vector constructs, alphavirus replicon particles expressing one or more antigens derived from one or more respiratory pathogens as well as to method of making and using these immunogenic compositions.