The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Dec. 21, 2007
Applicants:
Michael P. Vitek, Cary, NC (US);
Dale J. Christensen, Cary, NC (US);
Jessica Oddo, Durham, NC (US);
Inventors:
Assignee:
COGNOSCI, INC., Research Triangle Park, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61K 49/00 (2006.01); A61B 5/00 (2006.01); C07K 7/00 (2006.01); C07K 9/00 (2006.01); C07K 14/00 (2006.01); C07K 14/81 (2006.01); C07K 14/775 (2006.01); G01N 33/483 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 38/1709 (2013.01); C07K 14/775 (2013.01);
Abstract
The present invention provides methods for modulating SET activity by contacting SET with a binding agent such as an ApoE peptide derivative. In one embodiment of the invention, a pharmaceutical composition capable of modulating SET activity is administered to a patient for the treatment of an inflammatory or neurological condition. In another embodiment of the invention, compounds efficacious for the treatment of inflammatory and neurological conditions are identified by screening for a binding agent capable of competing with or inhibiting the binding of an ApoE derivative to SET.