The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Aug. 20, 2013
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventor:
William G. Austen, Jr., Weston, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 63/00 (2006.01); A61K 35/35 (2015.01); A61L 27/18 (2006.01); A61L 27/38 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 35/35 (2013.01); A61L 27/18 (2013.01); A61L 27/3804 (2013.01); G01N 33/5014 (2013.01); G01N 33/5088 (2013.01);
Abstract
The present invention provides polymers for use in preventing damage to the membranes of cells in fat grafts. Mixing of a triblock copolymer such as poloxymer P188 with adipocytes or adipose tissue to be transplanted into a subject is thought to stabilize the membranes of the cells leading to more successful fat transplantation in soft tissue reconstruction or augmentation. Such methods may also be used in the transplantation of adult stem cells or other cells derived from fat tissue. Other agents such as lipoic acid may also be added to the polymer/cell compositions for cell transplantation.