The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 15, 2017
Filed:
Jun. 20, 2014
Inserm (Institut National DE LA Sante ET DE LA Recherche Medicale), Paris, FR;
Universite Paris Descartes, Paris, FR;
Universite Pierre ET Marie Curie (Paris 6), Paris, FR;
Assistance Publique-hopitaux DE Paris (Aphp), Paris, FR;
Nicolette Farman, Paris, FR;
Frederic Jaisser, Paris, FR;
Francine Behar-Cohen, Paris, FR;
Selin Aractingi, Paris, FR;
Van Tuan Nguyen, Paris, FR;
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), Paris, FR;
UNIVERSITE PARIS DESCARTES, Paris, FR;
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), Paris, FR;
ASSISTANCE PUBLIQUE-HOPITAUX DE PARIS (APHP), Paris, FR;
Abstract
The present invention relates to method and pharmaceutical compositions for preventing glucocorticoid-induced corneal or skin thinning. In particular, the present invention relates to a mineralocorticoid receptor antagonist for topical use in a method for preventing or reducing glucocorticoid-induced corneal or skin thinning in a subject in need thereof. The invention also relates to a topical pharmaceutical composition comprising an amount of at least one glucocorticoid and an amount of at least one mineralocorticoid receptor antagonist or inhibitor of MR expression for use in a method for treating an inflammatory skin disease or an inflammatory disease of the cornea or of the anterior segment of the eye in a subject in need thereof.