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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9730938 B1

PDFFull Text
Date of Patent:
Aug. 15, 2017

Filed:

Aug. 06, 2015

Bruton's tyrosine kinase inhibitor combinations and uses thereof

Applicants:

Pharmacyclics Llc, Sunnyvale, CA (US);

Janssen Pharmaceutica NV, Beerse, BE;

Inventors:

Hsu-Ping Kuo, Sunnyvale, CA (US);

Hsin-Kang Hsieh, San Jose, CA (US);

Betty Chang, Cupertino, CA (US);

Ling Xue, Beijing, CN;

Sriram Balasubramanian, North Wales, PA (US);

Leo Cheung, Fremont, CA (US);

Assignees:

Pharmacyclics LLC, Sunnyvale, CA (US);

Janssen Pharmaceutica NV, Beerse, BE;

Attorney:

Foley Hoag LLP

Primary Examiner:

Sahar Javanmard

Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61K 31/4164 (2006.01); A61K 31/4196 (2006.01); A61K 31/426 (2006.01); A61K 31/454 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01); A61K 38/19 (2006.01); A61K 38/20 (2006.01); A61K 38/21 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61K 31/4164 (2013.01); A61K 31/4196 (2013.01); A61K 31/426 (2013.01); A61K 31/454 (2013.01); A61K 38/005 (2013.01); A61K 38/191 (2013.01); A61K 38/2013 (2013.01); A61K 38/21 (2013.01); A61K 45/06 (2013.01);
Abstract

Disclosed herein are methods, compositions, and kits for treating a B-cell malignancy comprising administering a combination of a BTK inhibitor (e.g. ibrutinib) and a PIM inhibitor. Also disclosed herein are methods, compositions, and kits for treating a BTK-resistant B-cell malignancy comprising administering a combination of a BTK inhibitor (e.g. ibrutinib) and a PIM inhibitor.

Find Patent Forward Citations

Kuo, Hsu-Ping. (2017). Bruton's tyrosine kinase inhibitor combinations and uses thereof (U.S. Patent No. 9730938). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9730938

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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