The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2017
Filed:
Apr. 15, 2010
Massimiliano Corsi, Milan, IT;
Stephen Peter Fitzgerald, Antrim, GB;
John V. Lamont, Antrim, GB;
Paul Innocenzi, Antrim, GB;
Massimiliano Corsi, Milan, IT;
Stephen Peter Fitzgerald, Antrim, GB;
John V. Lamont, Antrim, GB;
Paul Innocenzi, Antrim, GB;
RANDOX LABORATORIES LTD., , GB;
Abstract
The invention relates to methods of diagnosing Alzheimer's disease (AD) in a subject and methods of determining the prognosis in patients with AD. The adhesion molecules P-selectin and L-selectin are described for the first time for use as biomarkers to aid in the diagnosis of AD. The invention further describes the use of one or more of L-selectin, MCP-1, IL-1α, IL-8 and IFN-γ to aid in the prognosis of either accelerated cognitive decline (ACD) or slow cognitive decline (SCD) in patients with AD.