The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2017

Filed:

Dec. 31, 2014
Applicant:

Flagship Biosciences, Llc, Westminster, CO (US);

Inventor:

Steven J. Potts, Anthem, AZ (US);

Assignee:

Flagship Biosciences, Inc., Westminster, CO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G06K 9/00 (2006.01); C12Q 1/68 (2006.01); G01N 33/569 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); G01N 33/56966 (2013.01); G01N 33/56972 (2013.01); G01N 2800/7014 (2013.01); G01N 2800/7038 (2013.01); G06K 9/00127 (2013.01); G06T 2207/30024 (2013.01);
Abstract

The instant disclosure describes a method for measuring and reporting vascularity in a biological tissue sample. The method generally includes: within a digital image of a tissue section, (i) identifying endothelial cells, lymphatic cells, or a combination thereof; (ii) mapping one or more proximity regions, each of the proximity regions defining an area between detected vessels and a first distance outwardly therefrom; and (iii) calculating one or more of: a vessel proximity score or a hypoxia score, wherein the vessel proximity score relates a composition of objects within the proximity regions, and wherein the hypoxia score relates a composition of tissue within or outside of the proximity regions, respectively.


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