The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2017
Filed:
Sep. 03, 2016
Applicant:
Trovagene, Inc., San Diego, CA (US);
Inventors:
Jason Poole, San Diego, CA (US);
Saege Handcock, San Diego, CA (US);
Karena Kosco, San Diego, CA (US);
Vlada Melnikova, San Diego, CA (US);
Peter Croucher, San Diego, CA (US);
Tim Lu, San Diego, CA (US);
Mark Erlander, San Diego, CA (US);
Errin Samuelsz, San Diego, CA (US);
Assignee:
Trovagene, Inc., San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); C12P 19/34 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6806 (2013.01); C12Q 1/686 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/16 (2013.01);
Abstract
The present disclosure relates to the enrichment of target nucleic acid sequences present in low-abundance relative to corresponding non-target or reference nucleic acid sequence in a sample. In particular, the methods allow for a substantially greater level of detection sensitivity of target sequence by orders of magnitude enrichment of a low-abundance sequence.