The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2017

Filed:

Apr. 21, 2015
Applicants:

The United States of America, As Represented BY the Secretary of Agriculture, Washington, DC (US);

Los Alamos National Security, Llc, Los Alamos, NM (US);

Inventors:

Eddie W Stover, Fort Pierce, FL (US);

Goutam Gupta, Santa Fe, NM (US);

Guixia Hao, Fort Pierce, FL (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/82 (2006.01); C07K 7/08 (2006.01); C07K 14/415 (2006.01);
U.S. Cl.
CPC ...
C12N 15/8281 (2013.01); C07K 7/08 (2013.01); C07K 14/415 (2013.01); C07K 2319/00 (2013.01);
Abstract

The generation of a chimeric protein containing a first domain encoding either a pro-thionon or thionin, a second domain encoding D4E1 or pro-D4E1, and a third domain encoding a peptide linker located between the first domain and second domain is described. Either the first domain or the second domain is located at the amino terminal of the chimeric protein and the other domain (second domain or first domain, respectively) is located at the carboxyl terminal. The chimeric protein has antibacterial activity. Genetically altered plants and their progeny expressing a polynucleotide encoding the chimeric protein resist diseases caused by bacteria.


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