The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2017
Filed:
Dec. 06, 2012
Applicants:
Ohio State Innovation Foundation, Columbus, OH (US);
Research Institute AT Nationwide Children's Hospital, Columbus, OH (US);
Inventors:
Arthur Burghes, Columbus, OH (US);
Paul Porensky, Worthington, OH (US);
Brian Kaspar, New Albany, OH (US);
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01); C07H 21/04 (2006.01); A61K 31/70 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01); A61K 31/7105 (2006.01); A61K 31/711 (2006.01); A61K 49/04 (2006.01); A61K 47/24 (2006.01); A61K 9/00 (2006.01); C12N 5/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/0085 (2013.01); A61K 31/711 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 47/24 (2013.01); A61K 49/0438 (2013.01);
Abstract
Disclosed are compositions comprising an antisense oligonucleotide and a non-ionic, low-osmolar contrast agent. Also disclosed are methods of delivering an antisense oligonucleotide to a target sire comprising incorporating the antisense oligonucleotide into a composition comprising a non-ionic, low-osmolar contrast agent. Also disclosed are methods of treating a neurodegenerative disease comprising administering one or more of the compositions disclosed herein.