The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2017

Filed:

Nov. 18, 2014
Applicant:

Drexel University, Philadelphia, PA (US);

Inventors:

Peter I. Lelkes, Cherry Hill, NJ (US);

Mengyan Li, Philadelphia, PA (US);

Anat Perets, Narberth, PA (US);

Honesto Poblete, Philadelphia, PA (US);

Philip Lazarovici, Jerusalem, IL;

Assignee:

Drexel University, Philadelphia, PA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61F 2/00 (2006.01); C12N 5/00 (2006.01); A61K 35/12 (2015.01); A61L 27/36 (2006.01); A61L 27/38 (2006.01); A61L 27/56 (2006.01); A61K 35/30 (2015.01); A61K 38/39 (2006.01); C12N 5/071 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0062 (2013.01); A61K 35/12 (2013.01); A61K 35/30 (2013.01); A61K 38/39 (2013.01); A61L 27/3633 (2013.01); A61L 27/3675 (2013.01); A61L 27/3683 (2013.01); A61L 27/38 (2013.01); A61L 27/56 (2013.01); C12N 5/0068 (2013.01); C12N 5/0686 (2013.01); C12N 2533/90 (2013.01);
Abstract

Methods of making a biologically active three-dimensional scaffold capable of supporting growth and differentiation of a cell are described. Biologically active three-dimensional scaffold made by the methods of the invention and an engineered tissue made from the scaffolds are described. Fibers of desired porosity can be obtained from non-structural ECM by lyophilization and/or electrospinning which can be useful for numerous tissue engineering applications requiring complex scaffolds, such as wound healing, artificial skin (burns), soft tissue replacement/repair and spinal cord injury.


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