The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2017

Filed:

Jul. 27, 2012
Applicants:

Toyomasa Katagiri, Tokushima, JP;

Takuya Tsunoda, Kanagawa, JP;

Inventors:

Toyomasa Katagiri, Tokushima, JP;

Takuya Tsunoda, Kanagawa, JP;

Assignees:

TOKUSHIMA UNIVERSITY, Tokushima, JP;

ONCOTHERAPY SCIENCE, INC., Kanagawa, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/06 (2006.01); C07K 7/04 (2006.01); C07K 14/47 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); C12N 9/48 (2006.01); A61K 31/138 (2006.01); A61K 38/17 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4705 (2013.01); A61K 31/138 (2013.01); A61K 38/1709 (2013.01); C12N 9/485 (2013.01); G01N 33/5011 (2013.01); G01N 33/57484 (2013.01); A61K 38/00 (2013.01); G01N 2333/4704 (2013.01); G01N 2333/95 (2013.01); G01N 2500/02 (2013.01);
Abstract

Provided is a novel cancer-treating agent which can be used as a novel choice for the treatment of cancer. Specifically provided are: a peptide that inhibits binding of ERAP1 polypeptide to PHB2 polypeptide, which comprises a binding site of the ERAP1 polypeptide to the PHB2 polypeptide, and a pharmaceutical composition comprising the peptide. In addition, provided is a method for screening a drug candidate for treating and/or preventing cancer using inhibition of the binding of the ERAP1 polypeptide to PP1α polypeptide, PKA polypeptide or PKB polypeptide as an index.


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