The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2017
Filed:
Jun. 20, 2014
Lupin Limited, Mumbai, Maharashtra, IN;
Nageswara Rao Irlapati, Maharashtra, IN;
Nilesh Raghunath Khedkar, Maharashtra, IN;
Ravindra Babanrao Jape, Maharashtra, IN;
Rahul Shripad Nandurdikar, Maharashtra, IN;
Zubair Abdul Wajid Shaikh, Maharashtra, IN;
Neelima Sinha, Maharashtra, IN;
Venkata P. Palle, Maharashtra, IN;
Rajender Kumar Kamboj, Maharashtra, IN;
LUPIN LIMITED, Mumbai, IN;
Abstract
The invention relates to compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium release-activated calcium (CRAC) channel. The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium release-activated calcium (CRAC) channel modulators. wherein, ring D is Formula (a) or Formula (b): A and B, which may be same or different, are independently CRor N; Y is CRor N; L is selected from —NRC(O)—, —C(O)NR— and —NRCRR—; Rand Rare independently hydrogen, halogen or substituted or unsubstituted alkyl; ring E is selected from the Formula (i) to (vii).