The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2017

Filed:

Mar. 19, 2014
Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Matthew Lloyd Childers, Medfield, MA (US);

Christopher Dinsmore, Newton, MA (US);

Peter Fuller, Ashland, MA (US);

David Guerin, Natick, MA (US);

Jason David Katz, Newton, MA (US);

Qinglin Pu, Needham, MA (US);

Mark E. Scott, Andover, MA (US);

Christopher F. Thompson, Arlington, MA (US);

Hongjun Zhang, Newton, MA (US);

Danielle Falcone, Brookline, MA (US);

Luis Torres, Norwood, MA (US);

Jason Brubaker, Cambridge, MA (US);

Hongbo Zeng, Westford, MA (US);

Jiaqiang Cai, Shanghai, CN;

Xiaoxing Du, Shanghai, CN;

Chonggang Wang, Shanghai, CN;

Yunfeng Bai, Beijing, CN;

Norman Kong, Beijing, CN;

Yumei Liu, Beijing, CN;

Zhixiang Zheng, Beijing, CN;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 519/00 (2013.01);
Abstract

Compounds of formula I are provided, which are JAK inhibitors and are useful for the treatment of JAK-mediated diseases such as rheumatoid arthritis, asthma, COPD and cancer.


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