The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 08, 2017
Filed:
Jan. 22, 2016
Applicant:
Glaxosmithkline Intellectual Property Development Limited, Brentford, Middlesex, GB;
Inventors:
Alan Hornsby Davidson, Abingdon, GB;
David Festus Charles Moffat, Abingdon, GB;
Francesca Ann Day, Abingdon, GB;
Alastair David Graham Donald, Oxfordshire, GB;
Assignee:
GlaxoSmithKline Intellectual Property Development Limited, Brentford, Middlesex, GB;
Primary Examiner:
Int. Cl.
CPC ...
C07C 259/06 (2006.01); C07D 211/58 (2006.01); C07D 211/34 (2006.01); C07C 311/19 (2006.01); C07D 213/56 (2006.01); C07D 215/22 (2006.01); C07D 241/04 (2006.01); C07D 333/70 (2006.01); C07D 409/12 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07C 259/06 (2013.01); C07C 311/19 (2013.01); C07D 211/34 (2013.01); C07D 211/58 (2013.01); C07D 213/56 (2013.01); C07D 215/22 (2013.01); C07D 241/04 (2013.01); C07D 333/70 (2013.01); C07D 409/12 (2013.01); C07D 471/04 (2013.01); C07C 2101/08 (2013.01); C07C 2101/14 (2013.01);
Abstract
Compounds of formula (I) inhibit HDAC activity: wherein A, B and D independently represent ═C— or ═N—; W is a divalent radical —CH═CH— or CHCH—; Ris an ester group; Ris the side chain of a natural or non-natural alpha-amino acid; z is 0 or 1; and Y, L, and Xare as defined in the claims.