The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2017

Filed:

Sep. 27, 2010
Applicants:

Michael Austin, Philadelphia, PA (US);

Parikshit A. Deshpande, Princeton, NJ (US);

Alexey Sharonov, Drexel Hill, PA (US);

Valeriy Bogdanov, Philadelphia, PA (US);

Inventors:

Michael Austin, Philadelphia, PA (US);

Parikshit A. Deshpande, Princeton, NJ (US);

Alexey Sharonov, Drexel Hill, PA (US);

Valeriy Bogdanov, Philadelphia, PA (US);

Assignee:

BIONANO GENOMICS, INC., San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/558 (2006.01); B82Y 30/00 (2011.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
B82Y 30/00 (2013.01); G01N 21/645 (2013.01); G01N 33/558 (2013.01);
Abstract

Provided are devices and methods for polymer analysis, in which labeled polymers are translocated along nanochannels that have illuminated detection regions within. As a labeled polymer translocates along the nanochannel and the labels pass over the illuminated detection regions, the labels become detectable (e.g., where different labels fluoresce in response to different wavelengths present at different illumination regions), and the user generates a spatial map of the location of the various labels along the length of the polymer. The location of the labels is then correlated to one or more structural characteristics of the polymer.


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