The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9724381 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 08, 2017

Filed:

Oct. 02, 2014
Applicants:

The Administrators of the Tulane Educational Fund, New Orleans, LA (US);

Mcgill University, Montreal, CA;

Inventors:

Cyril Y. Bowers, New Orleans, LA (US);

David H. Coy, New Orleans, LA (US);

Gloria S. Tannenbaum, Hampstead, CA;

Assignees:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/22 (2006.01); A61K 38/10 (2006.01); A61K 38/08 (2006.01);
U.S. Cl.
CPC ...
A61K 38/10 (2013.01); A61K 38/08 (2013.01); A61K 38/22 (2013.01);
Abstract

The invention provides methods for treatment, prevention or management of obesity, obesity related disorders, diabetes mellitus, and metabolic syndrome in a subject by administering a ghrelin O-acyltransferase (GOAT) inhibitor and/or a ghrelin receptor antagonist to the subject. The invention also provides ghrelin receptor antagonists of formula (VII): A-A-A-Gly-Ser-A-Phe-Leu-A-A-A-A, wherein each of A, A, and Ais independently absent, an amino acid, or an amino protecting group; each of A, A, A, and Ais independently absent or an amino acid; and Ais a serine conjugated with a —C(O)C-Calky or a diaminopropionic acid conjugated with a —C(O)C-Calkyl group, provided that at least one of A, A, or Ais present.


Find Patent Forward Citations

Bowers, Cyril. (2017). Methods of inhibiting the ghrelin/growth hormone secretatogue receptor pathway and uses thereof (U.S. Patent No. 9724381). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9724381

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