The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 08, 2017

Filed:

Sep. 19, 2016
Applicants:

Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, CN;

Shanghai Haihe Pharmaceutical Co., Ltd., Shanghai, CN;

Inventors:

Chunhao Yang, Shanghai, CN;

Linghua Meng, Shanghai, CN;

Yanhong Chen, Shanghai, CN;

Xiang Wang, Shanghai, CN;

Cun Tan, Shanghai, CN;

Jiapeng Li, Shanghai, CN;

Jian Ding, Shaghai, CN;

Yi Chen, Shanghai, CN;

Attorney:
Int. Cl.
CPC ...
A61K 31/53 (2006.01); A61K 31/5377 (2006.01); C07D 419/04 (2006.01); A61P 35/00 (2006.01); A61K 31/5386 (2006.01); C07D 419/14 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/53 (2013.01); A61K 31/5386 (2013.01); C07D 419/04 (2013.01); C07D 419/14 (2013.01);
Abstract

The present invention relates to a pyrrolo[2,1-f][1,2,4]triazine compound, an isomer thereof or a pharmaceutically acceptable salt, ester or hydrate thereof, and a preparation method and application thereof. The pyrrolo[2,1-f][1,2,4]triazine compound has a structure expressed in general formula (I). The pyrrolo[2,1-f][1,2,4]triazine compound expressed in general formula (I) can inhibit a phosphatidylinositol-3 kinase (PI3K) signal pathway, thereby being used to prepare medicine for treating phosphatidylinositol-3 kinase related diseases such as cancer.


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