The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2017

Filed:

Jun. 23, 2014
Applicant:

Ventana Medical Systems, Inc., Tucson, AZ (US);

Inventors:

Jerome W. Kosmeder, II, Tucson, AZ (US);

Mark Lefever, Oro Valley, AZ (US);

Donald Johnson, Oro Valley, AZ (US);

Michael Farrell, Tucson, AZ (US);

Zhanna Zhilina, Tucson, AZ (US);

Christopher Bieniarz, Tucson, AZ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); C07D 495/04 (2006.01); G01N 33/532 (2006.01); G01N 33/533 (2006.01); G01N 33/58 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5308 (2013.01); C07D 495/04 (2013.01); C12Q 1/6804 (2013.01); C12Q 1/6841 (2013.01); C12Q 1/6886 (2013.01); G01N 33/532 (2013.01); G01N 33/533 (2013.01); G01N 33/58 (2013.01); G01N 33/582 (2013.01); G01N 33/583 (2013.01); Y10S 435/961 (2013.01); Y10S 530/807 (2013.01);
Abstract

A method for performing a multiplexed diagnostic assay, such as for two or more different targets in a sample, is described. One embodiment comprised contacting the sample with two or more specific binding moieties that bind specifically to two or more different targets. The two or more specific binding moieties are conjugated to different haptens, and at least one of the haptens is an oxazole, a pyrazole, a thiazole, a nitroaryl compound other than dinitrophenyl, a benzofurazan, a triterpene, a urea, a thiourea, a rotenoid, a coumarin, a cyclolignan, a heterobiaryl, an azo aryl, or a benzodiazepine. The sample is contacted with two or more different anti-hapten antibodies that can be detected separately. The two or more different anti-hapten antibodies may be conjugated to different detectable labels.


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