The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2017

Filed:

Sep. 09, 2009
Applicants:

Srabani Bhaumik, Niskayuna, NY (US);

Sanjiv Sam Gambhir, Portola Valley, CA (US);

Ramasamy Paulmurugan, Mountain View, CA (US);

Shahriar Yaghoubi, Palo Alto, CA (US);

Byeong-cheol Ahn, Daegu, KR;

Natesh Parashurama, San Mateo, CA (US);

Inventors:

Srabani Bhaumik, Niskayuna, NY (US);

Sanjiv Sam Gambhir, Portola Valley, CA (US);

Ramasamy Paulmurugan, Mountain View, CA (US);

Shahriar Yaghoubi, Palo Alto, CA (US);

Byeong-Cheol Ahn, Daegu, KR;

Natesh Parashurama, San Mateo, CA (US);

Assignee:

General Electric Company, Niskayuna, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12Q 1/68 (2006.01); C12N 15/10 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6897 (2013.01); C12N 15/1086 (2013.01); C12N 15/85 (2013.01); C12N 2830/008 (2013.01); C12N 2830/20 (2013.01); C12N 2840/20 (2013.01);
Abstract

An expression vector, comprising a first reporter nucleic acid sequence operably linked to a first expression control sequence comprising a promoter; and a second reporter nucleic acid sequence operably linked to a second expression control sequence that comprises a response element that is activated or inactivated as one or more of the cells differentiate or dedifferentiate. Methods and kits for imaging and monitoring stem cells comprising the expression vector are also provided.


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