The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2017

Filed:

Nov. 16, 2015
Applicants:

Sumitomo Rubber Industries, Ltd., Kobe-shi, Hyogo, JP;

Osaka University, Suita-shi, Osaka, JP;

Inventors:

Haruhiko Yamaguchi, Kobe, JP;

Yukino Inoue, Kobe, JP;

Keiji Takagi, Kobe, JP;

Kazuhisa Fushihara, Kobe, JP;

Toshiya Muranaka, Suita, JP;

Keiko Suzuki, Suita, JP;

Kanako Kobayashi, Suita, JP;

Assignees:

SUMITOMO RUBBER INDUSTRIES, LTD., Kobe-shi, Hyogo, JP;

OSAKA UNIVERSITY, Suita-shi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 5/00 (2006.01); C12N 15/82 (2006.01);
U.S. Cl.
CPC ...
C12P 5/007 (2013.01); C12N 15/8243 (2013.01); C12P 5/002 (2013.01);
Abstract

The present invention provides a method of increasing production of amorpha-4,11-diene and a method of increasing production of natural rubber. The present invention relates to a method of increasing production of amorpha-4,11-diene which includes the step of attaching an enzyme inhibitor tointo which has been introduced a gene encoding amorphadiene synthase. The enzyme inhibitor inhibits at least one enzyme other than amorphadiene synthase, that catalyzes an enzymatic reaction in which farnesyl diphosphate acts as a substrate. The present invention also relates to a method of increasing production of natural rubber which includes the step of attaching an enzyme inhibitor to a rubber-producing plant. The enzyme inhibitor inhibits at least one enzyme other than enzymes involved in natural rubber synthesis, that catalyzes an enzymatic reaction in which farnesyl diphosphate acts as a substrate.


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