The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9719090 B1

PDF
Full Text
Expired
Date of Patent:
Aug. 01, 2017

Filed:

Dec. 20, 2013
Applicant:

The Board of Trustees of the Leland Stanford Junior University, Stanford, CA (US);

Inventors:

Bingwei Lu, Stanford, CA (US);

Stephan Gehrke, Mountain View, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 15/113 (2010.01); A61K 31/7105 (2006.01); C12N 5/0793 (2010.01); A61K 45/06 (2006.01); A61K 35/30 (2015.01); A61K 31/13 (2006.01); A61K 31/198 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 31/13 (2013.01); A61K 31/198 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); A61K 35/30 (2013.01); A61K 45/06 (2013.01); C12N 5/0619 (2013.01); C12N 2310/14 (2013.01); C12N 2320/30 (2013.01); C12N 2501/60 (2013.01); C12N 2501/998 (2013.01); C12N 2503/02 (2013.01); C12N 2506/1307 (2013.01);
Abstract

Methods and compositions are provided for the treatment of a mitochondrial disease in an individual with the mitochondrial disease. Aspects of the methods include administering an inhibitor of a Pumilio-like protein and/or an inhibitor of a serine/arginine-rich family of pre-mRNA splicing factor (SR) protein to a subject. Also provided are methods, compositions, systems and kits for transdifferentiating target cells to neurons, which find use in producing neurons for the development of new therapies, for experimental evaluation, as a source of lineage- and cell-specific products, and the like, for example, for use in treating human disorders of the CNS.


Find Patent Forward Citations

Lu, Bingwei. (2017). Methods of trans-differentiating a terminally differentiated target cell to a neuron (U.S. Patent No. 9719090). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9719090

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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