The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2017
Filed:
Oct. 11, 2011
Davide Bianchi, Milan, IT;
Marco Valetti, Seregno, IT;
Paola Bazza, Villasanta, IT;
Nicolò Miraglia, Buccinasco, IT;
Ermanno Valoti, Dalmine, IT;
Davide Bianchi, Milan, IT;
Marco Valetti, Seregno, IT;
Paola Bazza, Villasanta, IT;
Nicolò Miraglia, Buccinasco, IT;
Ermanno Valoti, Dalmine, IT;
Gnosis S.p.A., Desio, IT;
Abstract
A process for the preparation of a chondroitin sulphate salt with an average molecular weight (Mw) of 10-30 kDa via chemical sulphation of an unsulphated chondroitin backbone is provided. The unsulphated chondroitin can be obtained by acid hydrolysis of a capsular polysaccharide K4 made directly fromstrain O5:K4:H4 or directly produced from a genetically modified strain of. Sulphation of the N-acetyl-D-galactosamine residue at position 4 or 6 takes place simultaneously in the same polysaccharide chain, simulating the sulphation pattern observed in natural chondroitin sulphate.