The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2017

Filed:

Feb. 26, 2014
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Timothy J. Deming, Los Angeles, CA (US);

Jessica R. Kramer, Oakland, CA (US);

April R. Rodriguez, Marina Del Rey, CA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08G 69/48 (2006.01); A61K 47/42 (2017.01); C08G 69/10 (2006.01); C08G 69/42 (2006.01); A61K 47/34 (2017.01); A61K 9/127 (2006.01);
U.S. Cl.
CPC ...
C08G 69/48 (2013.01); A61K 9/1273 (2013.01); A61K 47/34 (2013.01); A61K 47/42 (2013.01); C08G 69/10 (2013.01); C08G 69/42 (2013.01);
Abstract

Methods for preparation of novel amphiphilic derivatives of thioether containing block copolypeptides with narrow chain length distributions are described. These block copolymers can be chemically modified by oxidation and alkylation of the thioether containing residues. These materials generate self-assembled micelles, vesicles and hydrogels, or emulsions with oil phases. These assemblies can be used to encapsulate and delivery therapeutic molecules. The assemblies can be taken up by cells to release molecules from the assemblies.


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