The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2017

Filed:

Feb. 10, 2011
Applicants:

Volkhard Lindner, South Portland, ME (US);

Ilka Pinz, Limington, ME (US);

Julia Patrizia Stohn, Biddeford, ME (US);

Inventors:

Volkhard Lindner, South Portland, ME (US);

Ilka Pinz, Limington, ME (US);

Julia Patrizia Stohn, Biddeford, ME (US);

Assignee:

Maine Medical Center, Scarborough, ME (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/18 (2006.01); A61K 38/17 (2006.01); C07K 14/47 (2006.01); C07K 14/78 (2006.01); G01N 33/53 (2006.01); G01N 33/577 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C07K 16/18 (2013.01); A61K 38/1709 (2013.01); C07K 14/4703 (2013.01); C07K 14/78 (2013.01); C07K 2317/34 (2013.01); G01N 33/53 (2013.01); G01N 33/577 (2013.01); G01N 33/68 (2013.01);
Abstract

The invention provides methods for the treatment of coronary heart disease, peripheral vascular disease, stroke, and ischemia featuring agents that interfere with the expression or activity of Cthrc1. The invention also provides the use of Cthrc1 peptide as a therapeutic agent for the treatment of acute or chronic cardiac deficiencies. The invention further provides detection and monitoring of Cthrc1 peptide in blood or serum to assess or monitor cardiac function.


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