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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9718853 B1

PDFFull Text
Expired
Date of Patent:
Aug. 01, 2017

Filed:

Jan. 25, 2016

Anhydrous polymorphs of [(2r,3s,4r,5r)-5-(6-(cyclopentylamino)-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)] methyl nitrate and processes of preparation thereof

Applicant:

Inotek Pharmaceuticals Corporation, Lexington, MA (US);

Inventor:

William K. McVicar, Sudbury, MA (US);

Assignee:

Inotek Pharmaceuticals Corporation, Lexington, MA (US);

Attorneys:

Nelson Mullins Riley & Scarborough LLP

Jane E. Remillard, Esq.

Cynthia L. Kanik

Primary Examiner:

Lawrence E Crane

Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); C07H 19/20 (2006.01); C07H 19/167 (2006.01); C07H 19/173 (2006.01); C07H 19/16 (2006.01); C07H 1/06 (2006.01);
U.S. Cl.
CPC ...
C07H 19/16 (2013.01); C07H 1/06 (2013.01); C07H 19/167 (2013.01);
Abstract

The present invention provides novel anhydrous polymorph forms of [(2R,3S,4R,5R)-5-(6-(cyclopentylamino)-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)]methyl nitrate (compound A), a selective adenosine Areceptor agonist with a number of therapeutic uses including the treatment of elevated intra-ocular pressure. Also provided are methods for the preparation of the anhydrous polymorphic forms of compound A, pharmaceutical compositions and methods of treatment.

Find Patent Forward Citations

McVicar, William. (2017). Anhydrous polymorphs of [(2r,3s,4r,5r)-5-(6-(cyclopentylamino)-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)] methyl nitrate and processes of preparation thereof (U.S. Patent No. 9718853). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9718853

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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