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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9718841 B1

PDFFull Text
Expired
Date of Patent:
Aug. 01, 2017

Filed:

Apr. 16, 2015

Bicyclic pyrazolone compounds and methods of use

Applicants:

Calitor Sciences, Llc, Newbury Park, CA (US);

Sunshine Lake Pharma Co., Ltd., Dongguan, Guangdong, CN;

Inventors:

Ning Xi, Newbury Park, CA (US);

Yanjun Wu, Dongguan, CN;

Assignees:

CALITOR SCIENCES, LLC, Newbury Park, CA (US);

SUNSHINE LAKE PHARMA CO., LTD., Dongguan, Guangdong, CN;

Attorneys:

Kam W. Law

Squire Patton Boggs (US) LLP

Primary Examiner:

Timothy R Rozof

Int. Cl.
CPC ...
C07D 498/04 (2006.01); C07D 471/04 (2006.01); C07D 487/04 (2006.01); A61K 31/437 (2006.01); A61K 31/4439 (2006.01); A61K 31/444 (2006.01); A61K 31/5383 (2006.01); A61K 45/06 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C07D 498/04 (2013.01); A61K 31/437 (2013.01); A61K 31/444 (2013.01); A61K 31/4439 (2013.01); A61K 31/5383 (2013.01); A61K 45/06 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C12N 9/12 (2013.01); C12Y 207/10001 (2013.01);
Abstract

The present invention provides substituted bicyclic pyrazolone compounds, which are used to inhibit or modulate the activity of receptor tyrosine kinases, especially Axl, Mer, c-Met and Ron. The invention also provides pharmaceutical compositions comprising the compound disclosed herein, and a method of preventing, treating or lessening the severity of a proliferative disorder in a patient with the compounds or the pharmaceutical compositions disclosed herein.

Find Patent Forward Citations

Xi, Ning. (2017). Bicyclic pyrazolone compounds and methods of use (U.S. Patent No. 9718841). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9718841

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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