The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2017
Filed:
Aug. 22, 2016
Applicant:
Eli Lilly and Company, Indianapolis, IN (US);
Inventors:
Deqi Guo, Carmel, IN (US);
Anh-Quan Hannah Nguyen, Carmel, IN (US);
Michael Enrico Richett, Indianapolis, IN (US);
Assignee:
Eli Lilly and Company, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 495/04 (2006.01); A61K 31/5377 (2006.01); A61K 31/337 (2006.01); A61K 31/282 (2006.01); A61K 31/55 (2006.01); A61K 33/24 (2006.01); A61K 31/7068 (2006.01); A61K 31/444 (2006.01); A61K 31/4745 (2006.01);
U.S. Cl.
CPC ...
C07D 495/04 (2013.01); A61K 31/282 (2013.01); A61K 31/337 (2013.01); A61K 31/444 (2013.01); A61K 31/4745 (2013.01); A61K 31/5377 (2013.01); A61K 31/55 (2013.01); A61K 31/7068 (2013.01); A61K 33/24 (2013.01);
Abstract
The present invention relates to compounds that inhibit activity of the histone lysine methyltransferase, Enhancer of Zeste Homolog 2 (EZH2), pharmaceutical compositions comprising the compounds, and methods of using the compounds to treat cancer, such as hematologic and solid tumors.