The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 01, 2017

Filed:

Aug. 18, 2014
Applicants:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Duane Demong, Kenilworth, NJ (US);

Thomas J. Greshock, West Point, PA (US);

Ronald K. Chang, West Point, PA (US);

Xing Dai, Kenilworth, NJ (US);

Hong Liu, Kenilworth, NJ (US);

John A. Mccauley, West Point, PA (US);

Wei LI, Kenilworth, NJ (US);

Kallol Basu, Kenilworth, NJ (US);

Jack D. Scott, Kenilworth, NJ (US);

Michael Miller, Kenilworth, NJ (US);

Inventors:

Duane DeMong, Somerset, NJ (US);

Thomas J. Greshock, Collegeville, PA (US);

Ronald K. Chang, Oreland, PA (US);

Xing Dai, Cranford, NJ (US);

Hong Liu, Hillsborough, NJ (US);

John A. McCauley, Maple Glen, PA (US);

Wei Li, Belle Mead, NJ (US);

Kallol Basu, Piscataway, NJ (US);

Jack D. Scott, Scotch Plains, NJ (US);

Michael Miller, Scotch Plains, NJ (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/44 (2006.01); C07D 471/04 (2006.01); C07D 498/04 (2006.01); C07D 519/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention is directed to azaindazole compounds which are potent inhibitors of LRRK2 kinase and useful in the treatment or prevention of diseases in which the LRRK2 kinase is involved, such as Parkinson's Disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which LRRK-2 kinase is involved.


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