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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9718790 B1

PDFFull Text
Date of Patent:
Aug. 01, 2017

Filed:

Aug. 09, 2011

Triazine derivative and pharmaceutical composition having an analgesic activity comprising the same

Applicants:

Hiroyuki Kai, Toyonaka, JP;

Tohru Horiguchi, Toyonaka, JP;

Kentaro Asahi, Toyonaka, JP;

Yasuhiko Fujii, Toyonaka, JP;

Inventors:

Hiroyuki Kai, Toyonaka, JP;

Tohru Horiguchi, Toyonaka, JP;

Kentaro Asahi, Toyonaka, JP;

Yasuhiko Fujii, Toyonaka, JP;

Assignee:

SHIONOGI & CO., LTD., Osaka, JP;

Attorney:

Finnegan, Henderson, Farabow, Garrett & Dunner, LLP

Primary Examiner:

Irina Neagu

Int. Cl.
CPC ...
C07D 251/46 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 413/12 (2006.01); C07D 417/12 (2006.01); A61P 25/02 (2006.01); C07D 401/06 (2006.01); C07D 403/06 (2006.01); C07D 405/06 (2006.01); C07D 405/12 (2006.01); C07D 409/06 (2006.01); C07D 413/06 (2006.01); C07D 413/14 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); C07D 251/52 (2006.01); C07D 403/04 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 251/46 (2013.01); C07D 251/52 (2013.01); C07D 401/06 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 403/06 (2013.01); C07D 403/12 (2013.01); C07D 405/06 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/06 (2013.01); C07D 413/06 (2013.01); C07D 413/12 (2013.01); C07D 413/14 (2013.01); C07D 417/06 (2013.01); C07D 417/12 (2013.01); C07D 417/14 (2013.01);
Abstract

The present invention provides novel compounds having a P2Xand/or P2Xreceptor antagonistic effect. A pharmaceutical composition having an analgesic effect or an improving effect of urination disorder comprising a compound of the formula (I): whereinRand Rare taken together to form a bond; Rand Rand/or Rand Rare taken together to form oxo or the like; Ris hydrogen, substituted or unsubstituted alkyl or the like;Ris —(CRR)—R; Rand Rare hydrogen, substituted or unsubstituted alkyl or the like; Ris substituted or unsubstjtuted cycloalkyl or the like; n is an integer of 1 to 4; —Ris —X—R; —X— is —O—, —S— or the like; Ris substituted or unsubstituted cycloalkyl or the like,or its pharmaceutically acceptable salt or a solvate thereof.

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