The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2017
Filed:
Apr. 18, 2016
Applicants:
Duke University, Durham, NC (US);
Chaperone Therapeutics, Inc, Durham, NC (US);
Inventors:
Dennis J. Thiele, Chapel Hill, NC (US);
Daniel W. Neef, Durham, NC (US);
Jose Serafin Mendoza, Chapel Hill, NC (US);
Assignees:
DUKE UNIVERSITY, Durham, NC (US);
CHAPERONE THERAPEUTICS, INC., Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/38 (2006.01); C07D 231/40 (2006.01); A61K 31/415 (2006.01); A61K 31/4155 (2006.01); A61K 31/426 (2006.01); A61K 45/06 (2006.01); C07D 277/42 (2006.01); C07D 277/60 (2006.01); C07D 409/04 (2006.01); C07K 14/47 (2006.01); C07C 211/01 (2006.01); C07D 277/38 (2006.01); C07D 405/14 (2006.01); C07D 413/12 (2006.01); C07C 211/29 (2006.01); C07D 277/46 (2006.01);
U.S. Cl.
CPC ...
C07D 231/40 (2013.01); A61K 31/415 (2013.01); A61K 31/4155 (2013.01); A61K 31/426 (2013.01); A61K 45/06 (2013.01); C07C 211/01 (2013.01); C07C 211/29 (2013.01); C07D 231/38 (2013.01); C07D 277/38 (2013.01); C07D 277/42 (2013.01); C07D 277/46 (2013.01); C07D 277/60 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 413/12 (2013.01); C07K 14/47 (2013.01);
Abstract
The present invention relates to substituted pyrazole compounds, methods for their discovery, and their research and therapeutic uses, as well as pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, prodrugs, mixtures (including both R and S enantiomeric forms and racemic mixtures thereof) and pharmaceutical formulations thereof.