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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9718782 B1

PDFFull Text
Date of Patent:
Aug. 01, 2017

Filed:

Sep. 17, 2014

Trka kinase inhibitors, compositions and methods thereof

Applicant:

Merck Sharp & Dohme Corp, Rahway, NJ (US);

Inventors:

Andrew J. Cooke, Doylestown, PA (US);

Craig A. Stump, Pottstown, PA (US);

Xu-Fang Zhang, Dresher, PA (US);

Chun Sing Li, Shanghai, CN;

Qinghua Mao, Shanghai, CN;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:

Sylvia A. Ayler

John C. Todaro

Primary Examiner:

Irina Neagu

Int. Cl.
CPC ...
C07D 213/75 (2006.01); C07D 405/04 (2006.01); C07D 487/04 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 513/04 (2006.01); C07D 471/04 (2006.01); C07D 231/40 (2006.01); C07D 239/42 (2006.01); C07D 261/14 (2006.01); C07D 277/44 (2006.01); C07D 311/88 (2006.01); C07D 233/88 (2006.01); C07D 405/12 (2006.01); C07D 249/08 (2006.01); C07C 275/28 (2006.01); C07D 257/04 (2006.01); C07D 263/32 (2006.01); C07D 271/10 (2006.01); C07D 277/48 (2006.01); C07D 285/12 (2006.01); C07D 295/135 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 213/75 (2013.01); C07C 275/28 (2013.01); C07D 231/40 (2013.01); C07D 233/88 (2013.01); C07D 239/42 (2013.01); C07D 249/08 (2013.01); C07D 257/04 (2013.01); C07D 261/14 (2013.01); C07D 263/32 (2013.01); C07D 271/10 (2013.01); C07D 277/44 (2013.01); C07D 277/48 (2013.01); C07D 285/12 (2013.01); C07D 295/135 (2013.01); C07D 311/88 (2013.01); C07D 401/04 (2013.01); C07D 403/04 (2013.01); C07D 405/04 (2013.01); C07D 405/12 (2013.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The present invention is directed to benzyl urea compounds of formula (I) which are tropomyosin-related kinase (Trk) family protein kinase inhibitors, and hence may be useful in the treatment of pain, inflammation, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, a disease, disorder, injury, or malfunction relating to dysmyelination or demyelination or a disease or disorder associated with abnormal activities of nerve growth factor (NGF) receptor Trk-A, Trk-B and/or Trk-C.

Find Patent Forward Citations

Cooke, Andrew. (2017). Trka kinase inhibitors, compositions and methods thereof (U.S. Patent No. 9718782). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9718782

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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