The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2017
Filed:
Jan. 23, 2014
Fundação DE Amparo À Pesquisa DO Estado DE Minas Gerais-fapemig, Bairro São Pedro, Belo Horizonte, BR;
Universidade Federal DE Viçosa, Viçosa, BR;
Márcia Rogéria De Almeida, Viçosa, BR;
Abelardo Silva Junior, Viçosa, BR;
Juliana Lopes Rangel Fietto, Visçosa, BR;
Gustavo Costa Bressan, Viscçosa, BR;
Rafael Locatelli Salgado, Viçosa, BR;
Thiago Souza Onofre, Viçosa, BR;
Mariana Costa Fausto, Viçosa, BR;
Pedro Marcus Pereira Vidigal, Viçosa, BR;
Sthefany Patareli Kalks, Viçosa, BR;
Josicelli Souza Crispim, Viçosa, BR;
Roberta Amaziles Silva Leite, Viçosa, BR;
Jackson de Andrade Teixeira, Viçosa, BR;
Natália Fialho Gonzaga, Viçosa, BR;
Tiago Jaquel Zilch, Viçosa, BR;
Luiz Fernando Lino De Souza, Rio de Janeiro, BR;
Amanda Martins De Cruz Souza, Viçosa, BR;
Antônio De Morais Monteiro, Viçosa, BR;
FUNDAÇÃO DE AMPARO À PESQUISA DO ESTADO DE MG-FAPEMIG, Belo Horizonte, MG, BR;
UNIVERSIDADE FEDERAL DE VIÇOSA, Viçosa, MG, BR;
Abstract
The present invention relates to the preparation of the recombinant antigen of the viral capsid of Porcine circovirus 2 (PCV-2) and modifications thereof, upon expression in a prokaryotic system, purification in the monomer form, recovery of virus-like particles (VLPs) and their use in vaccine formulations, diagnostic kits and a system for quantifying in vaccine lots of the PCV-2 antigen by means of a capture ELISA assay. The antigens and vaccine formulations can be used in animal's immunization in programs for combatting PCV-2-associated diseases in conventional swine breeding systems, and represent alternatives to the commercially available vaccines. The ELISA kit can be used for testing the quality of commercial and/or experimental vaccines against PCV-2.