The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 01, 2017
Filed:
Aug. 21, 2013
Applicant:
The University of Chicago, Chicago, IL (US);
Inventors:
Jonathan Moss, Chicago, IL (US);
Mark Lingen, Oak Park, IL (US);
Patrick A. Singleton, Chicago, IL (US);
Joe G. N. Garcia, Chicago, IL (US);
Assignee:
THE UNIVERSITY OF CHICAGO, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/485 (2006.01); A61K 31/452 (2006.01); A61K 31/475 (2006.01); A61K 31/513 (2006.01); A61K 31/517 (2006.01); A61K 31/46 (2006.01); G01N 33/50 (2006.01);
U.S. Cl.
CPC ...
A61K 31/485 (2013.01); A61K 31/452 (2013.01); G01N 33/5011 (2013.01);
Abstract
Embodiments of the invention provide methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, as well as attenuating cancerous tumor growth and metastasis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.