The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2017
Filed:
Sep. 30, 2015
The Regents of the University of California, Oakland, CA (US);
Isis Pharmaceuticals, Inc., Carlsbad, CA (US);
Michael Oestergaard, Carlsbad, CA (US);
Punit P. Seth, Carlsbad, CA (US);
Shuling Guo, Carlsbad, CA (US);
Noriko Satake, Davis, CA (US);
Nitin Nitin, Davis, CA (US);
Joseph M. Tuscano, Davis, CA (US);
The Regents of the University of California, Oakland, CA (US);
Ionis Pharmaceuticals, Inc., Carlsbad, CA (US);
Abstract
The present disclosure provides compounds comprising modified oligonucleotides and anti-CD22 antibodies. Certain such modified oligonucleotides conjugated to anti-CD22 antibodies are useful for hybridizing to a complementary nucleic acid, including but not limited, to nucleic acids in a cell. In certain embodiments, hybridization results in modulation of the amount activity or expression of the target nucleic acid in a cell.