The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2017
Filed:
Oct. 28, 2014
Applicant:
Jiangsu Tasly Diyi Pharmaceutical Co., Ltd., Huai'an, CN;
Inventors:
Guocheng Wang, Tianjin, CN;
Wenzheng Liu, Tianjin, CN;
Yuzhe Gao, Tianjin, CN;
Hailong Yang, Tianjin, CN;
Qingwei Hou, Tianjin, CN;
Yu Zhang, Tianjin, CN;
Assignee:
Jiangsu Tasly Diyi Pharmaceutical Co., Ltd., Huai'an, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/4188 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); C07B 2200/13 (2013.01);
Abstract
Provided in the present invention are a new method for preparing the crystalline forms of Temozolomide and three types of crystalline form of Temozolomide by the method. Said method comprises the following steps: a Temozolomide is dissolved into dimethyl sulphoxide, a second organic solvent is added for recrystallization to prepare the crystalline forms of Temozolomide, wherein the second organic solvent is an alcohol, a ketone, a halohydrocarbon or an ester.