IDiyas

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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9714243 B1

PDFFull Text
Date of Patent:
Jul. 25, 2017

Filed:

Dec. 12, 2013

4-pyridinonetriazine derivatives as hiv integrase inhibitors

Applicant:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Inventors:

Mark W. Embrey, Harleysville, PA (US);

Thomas H. Graham, Scotch Plains, NJ (US);

Abbas Walji, Lansdale, PA (US);

Sherman T. Waddell, Wesetfield, NJ (US);

Tao Yu, Edison, NJ (US);

Yonglian Zhang, Metuchen, NJ (US);

Wensheng Liu, Edison, NJ (US);

Paul J. Coleman, Harleysville, PA (US);

John Wai, Harleysville, PA (US);

Thomas Steele, Schwenksville, PA (US);

Christina Di Marco, Lafayette Hill, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:

Nicole M. Beeler

Catherine D. Fitch

Primary Examiner:

Paul V Ward

Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/53 (2006.01); C07D 471/10 (2006.01); C07F 9/6521 (2006.01); A61K 31/675 (2006.01); A61K 31/55 (2006.01); A61K 31/4985 (2006.01); A61K 45/06 (2006.01); C07D 471/14 (2006.01); C07D 471/20 (2006.01); C07D 491/20 (2006.01); C07D 495/20 (2006.01); C07D 498/14 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4985 (2013.01); A61K 31/53 (2013.01); A61K 31/55 (2013.01); A61K 31/675 (2013.01); A61K 45/06 (2013.01); C07D 471/10 (2013.01); C07D 471/14 (2013.01); C07D 471/20 (2013.01); C07D 491/20 (2013.01); C07D 495/20 (2013.01); C07D 498/14 (2013.01); C07F 9/6521 (2013.01);
Abstract

The present invention relates to 4-Pyridinonetriazine Derivatives of Formula (I); and pharmaceutically acceptable salts thereof, wherein A, X, Y, R, R, Rand Rare as defined herein. The present invention also relates to compositions comprising at least one 4-Pyridinonetriazine Derivative, and methods of using the 4-Pyridinonetriazine Derivatives for treating or preventing HIV infection in a subject.

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