The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 25, 2017
Filed:
Dec. 21, 2015
Applicants:
Incyte Corporation, Wilmington, DE (US);
Incyte Holdings Corporation, Wilmington, DE (US);
Inventors:
Pingli Liu, Newark, DE (US);
Dengjin Wang, Wilmington, DE (US);
Yongzhong Wu, Chadds Ford, PA (US);
Ganfeng Cao, Newark, DE (US);
Michael Xia, Wilmington, DE (US);
Assignees:
Incyte Corporation, Wilmington, DE (US);
Incyte Holdings Corporation, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07F 5/02 (2006.01); C07D 403/14 (2006.01); C07D 487/04 (2006.01); C07F 5/04 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); C07D 403/14 (2013.01); C07D 487/04 (2013.01); C07F 5/025 (2013.01); C07F 5/04 (2013.01);
Abstract
This invention relates to processes and intermediates for making {1-{1-[3-fluoro-2-(trifluoromethyl)isonicotinoyl]piperidin-4-yl}-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidin-3-yl}acetonitrile, useful in the treatment of diseases related to the activity of Janus kinases (JAK) including inflammatory disorders, autoimmune disorders, cancer, and other diseases.