The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2017

Filed:

Jul. 08, 2014
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Thomas David McCarthy, Old Greenwich, CT (US);

Alan Naylor, Royston Hertfordshire, GB;

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 217/26 (2006.01); A61K 31/44 (2006.01); C07H 13/10 (2006.01); C07H 13/04 (2006.01); C07H 17/02 (2006.01);
U.S. Cl.
CPC ...
C07D 217/26 (2013.01); C07H 13/04 (2013.01); C07H 13/10 (2013.01); C07H 17/02 (2013.01);
Abstract

The present invention relates generally to compounds that are useful in antagonizing the angiotensin II type 2 (AT) receptor. More particularly, the invention relates to substituted isoquinoline compounds and their use as ATreceptor antagonists. Pharmaceutical compositions comprising the compounds and their use in modulating the ATreceptor and therapies that require modulation of the ATreceptor are described.


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