The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2017

Filed:

Sep. 15, 2016
Applicant:

Bioinspire Technologies, Inc., Palo Alto, CA (US);

Inventors:

Dorna Hakimimehr, San Francisco, CA (US);

Raoul Bonan, Mirabel, CA;

Assignee:

BioInspire Technologies, Inc., Palo Alto, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61L 31/04 (2006.01); A61K 9/70 (2006.01); A61L 31/14 (2006.01); A61K 38/36 (2006.01); A61K 45/06 (2006.01); A61M 25/10 (2013.01); A61L 31/16 (2006.01); A61K 47/02 (2006.01); A61K 47/10 (2017.01); A61L 31/02 (2006.01); A61L 31/18 (2006.01);
U.S. Cl.
CPC ...
A61L 31/046 (2013.01); A61K 9/7007 (2013.01); A61K 9/7046 (2013.01); A61K 9/7084 (2013.01); A61K 38/363 (2013.01); A61K 38/4833 (2013.01); A61K 45/06 (2013.01); A61K 47/02 (2013.01); A61K 47/10 (2013.01); A61L 31/022 (2013.01); A61L 31/041 (2013.01); A61L 31/14 (2013.01); A61L 31/141 (2013.01); A61L 31/148 (2013.01); A61L 31/16 (2013.01); A61L 31/18 (2013.01); A61M 25/10 (2013.01); C12Y 304/21005 (2013.01); A61L 2300/216 (2013.01); A61L 2300/252 (2013.01); A61L 2300/254 (2013.01); A61M 2025/105 (2013.01);
Abstract

Methods and apparatus for a free-standing biodegradable patch suitable for medical applications, especially intravascular, minimally-invasive and intraoperative surgical applications are provided, wherein the patch comprises a free-standing film or device having a mixture of a solid fibrinogen component and a solid thrombin component that, when exposed to an aqueous environment, undergoes polymerization to form fibrin. In alternative embodiments the patch may comprise a solid fibrinogen component, with or without an inorganic calcium salt component. The patch may take a non-adherent form during delivery to a target location within a vessel or tissue, and thereafter may be activated to adhere to vessel wall or tissue, and may include a number of additives, including materials to improve the mechanical properties of the patch, or one or more therapeutic or contrast agents.


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