The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 25, 2017

Filed:

Feb. 28, 2017
Applicant:

Takeda Pharmaceutical Company Limited, Osaka-shi, Osaka, JP;

Inventors:

Tomomichi Futo, Osaka, JP;

Kazuhiro Saito, Osaka, JP;

Tetsuo Hoshino, Osaka, JP;

Masuhisa Hori, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 38/08 (2006.01);
U.S. Cl.
CPC ...
A61K 9/5089 (2013.01); A61K 9/5031 (2013.01); A61K 38/08 (2013.01);
Abstract

Sustained-release compositions wherein a water-soluble physiologically active peptide is substantially uniformly dispersed in a microcapsule comprised of a lactic acid polymer or a salt thereof, and the physiologically active substance is contained in an amount of 15 to 35 wt/wt % to the total microcapsules and weight-average molecular weight (Mw) of the lactic acid polymer is about 11,000 to about 27,000, which is characterized by having a high content of the physiologically active substance, and suppression of the initial excessive release within one day after the administration and a stable drug sustained-release over a long period of time, and method for producing the same.


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